https://doi.org/10.33698/NRF0238-Kumari   Khushboo Saini, Jaswinder Kaur Kalra

Abstract: Introduction: Pregnancy is being most precious and very important time in every woman’s life. But sometimes pregnancy is associated with complications. About 7–15 % of all pregnancies are complicated by hypertension. Pregnancy induced hypertension is one of the leading causes of maternal and neonatal mortality and morbidity. Objective: To assess selected maternal, fetal and neonatal outcomes among antenatal mothers with pregnancy-induced hypertension. Material and Method: The study design was descriptive. It was conducted among antenatal mothers above 20 weeks of gestation diagnosed with PIH, attending Antenatal Clinic, PGIMER, Chandigarh. The sample size was 50 and purposive sampling technique was used. Results: More than half of mothers(56%) of age 26-30 years and 64.5% had gestational age of 37-40 weeks. About two third of mothers (64.5%) terminated pregnancy by cesarean section and 9.7% had 1st degree perineal tear. More than half of mothers(61.2%) had normal blood pressure after delivery. Nearly half of babies (48.3%) had APGAR score 8 at 1 minute and 58.06% had APGAR score 9 at 5 minutes. More than half of mothers(54.8%)initiated breastfeeding within 6 hours and 32.2% babies had birth weight more than 2.5 kgs. About, 67.7% newborns were admitted in NICU and 32.5% were healthy. Conclusion :Maternal and neonatal outcomes were good , may be because antenatal mothers were registered, supervised and delivered in tertiary care institution under supervision of expert obstetricians, neonatologists and nurses. Hence resulted into healthy mothers and neonates.

Keywords:

Antenatal mother, pregnancy-induced hypertension.

Correspondence at

Dr. Avinash Kaur Rana Lecturer

National Institute of Nursing Education PGIMER, Chandigarh-160012

Introduction:

Hypertensive disorders of pregnancy are responsible for maternal and neonatal morbidity and mortality. Worldwide, it has been estimated that approximately 50,000 women die every year due to eclampsia.1 Hypertensive disorders of pregnancy affect 5-10% of all pregnancies, worldwide. The incidence of pre-eclampsia in nulliparous population ranges from 3 to 10 percent worldwide. The incidence of eclampsia varies between developed and developing countries is 1:100. Incidence of PIH is 15.2% in India, while it is four times higher in primipara women than multipara. Pregnancy induced hypertension leads to complications in both mothers and babies. It is associated with increased risk of adverse fetal, neonatal and maternal outcomes, including preterm birth, intrauterine growth restriction (IUGR), perinatal death, acute renal or hepatic failure, antepartum hemorrhage, postpartum hemorrhage and maternal death.1

Objective :

To assess selected maternal, fetal and neonatal outcomes among antenatal mo t h e r s w i t h p r eg n an cy – i n d u ced hypertension

Materials and Methods:

The study design was descriptive. It was conducted among antenatal mothers above 20 weeks of gestation diagnosed with pregnancy induced hypertension in Antenatal Clinic (ANC), at Postgraduate Institute of Medical Education and Research ( PGIMER), Chandigarh. Purposive sampling technique was used. The sample size was 50. Written informed consent was taken from the subjects. Interview schedule was prepared to assess maternal, fetal and neonatal outcome of women having pregnancy Induced Hypertension. Ethical clearance was taken f rom Institute Ethics Committee. Participants were interviewed in clean labour room of PGI, Chandigarh as per interview schedule.

Results :

Table 1 depicts that more than half of mothers( 56%) of age 26- 30 years, educational status of 38% was graduate and above, most of them (90%) were housewives and middle class(58%), more than half of them (62%) were Hindus by religion, About 90% of them lived in nuclear family and 66% had rural habitat. Most of mothers (96%) were vegetarians.

Clinical profile of mothers

Table 2 depicts that 34 % had previous history of hypertension in their previous pregnancy. Family history of hypertension was present in 44% mothers. Nearly 20% suffered from minor disorders of pregnancy like nausea and vomiting. Nearly two third of mothers had pain in extremities during their present pregnancy. Majority of mothers (94%) had normal micturition and majority of them (90%) had normal per vaginal discharge. Presence of edema at feet was reported by 68% mothers.

Table 3 depicts that 64.5% mothers had gestational age of 37-40 weeks. About two third of mothers(64.5%) terminated pregnancy by cesarean section and 9.7% had 1st degree perineal tear. Majority of mothers (61.2%) had normal blood pressure after delivery.

Table 4 shows that 64.5% had gestational age of more than 37 weeks, 64.6% were male babies whereas 48.3% had APGAR score of 8 at 1 minute and 58.06% had APGAR score 9 at 5 minutes. More than half of mothers ( 54 . 8 %) initiated breastfeeding within 6 hours and 32.2% had birth weight more than 2.5 kgs. Two third Newborns ( 67.7% ) were admitted in NICU and 32.5% were healthy.

Table 1: Socio demographic profile of mothers

N =50

Variables Group

n =  50     (%)

Age (years)

20-25

26-30

31-35

36-45

07 (14)

23 (56)

11 (22)

09 (18)

Educational status of mother

Primary Secondary

Graduate and above

14 (28)

17 (34)

19 (38)

Educational status of husband

Primary Secondary

Graduate and above

08 (16)

22 (44)

20 (40)

Occupation of mother

Professional Skilled worker Housewife

03(6)

02 (4)

45 (90)

Occupation of husband

Professional

Clerical/shop owner/farmer Skilled worker

09 (18)

07 (14)

34 (68)

Per capita income (INR)#

Middle class(1733-2886) Lower middle class(866 -1732)

Lower class(<866)

29 (58)

17(34)

0 4(8)

Religion

Hindu Sikh/Muslim

31 (62)

19 (38)

Family type

Nuclear Joint

45 (90)

5 (10)

Habitat

Urban Rural

17 (34)

33 (66)

Dietary habits

Vegetarian Non vegetarian

48 (96)

2 (4)

 

#according to BG Prasad scale, 2015

 Discussion

Hypertensive disorders of pregnancy are one of major causes of deaths in pregnant mothers. These disorders complicate pregnancy, lead to major threats to mothers and their babies. Among them 7- 1 0 % o f p r e g n a n c i e s s u f f e r f r o m hypertensive disorders of pregnancy. It includes chronic hypertension, gestational hypertension, and a group of conditions associated with high blood pressure during pregnancy. Furthermore, these conditions remain one of the largest single causes of maternal and fetal morbidity and mortality.1 Pregnancy induced hypertension leads to complications in both mothers and babies. It is associated with increased risk of  adverse  fetal,  neonatal  and   maternal

Table 2: Clinical profile of mothers

N=50

 

Variables F (%)
History of past medical illness

 

Hypertension TB

Blood transfusion

Thyroid disorder Malaria

Renal disease Diabetes

Rheumatic fever Heart disease

No specic illness

 

17 (34)

05 (10)

05 (10)

03 (6)

04 (8)

03 (6)

02 (4)

02 (4)

01 (2)

08 (16)

Family history Hypertension Diabetes Malaria

TB

Multiple birth Mental illness

 

22 (44)

11 (22)

05 (10)

04 (8)

04 (8)

03 (6)

Minor disorders in pregnancy (digestion)

Vomiting

Nausea Constipation

 

33 (66)

10 (20)

07 (14)

Pain Extremities Back

Abdomen

 

31 (62)

11 (22)

08 (16)

Micturition

Normal Frequent

 

47 (94)

03 (6)

Discharge p/v

Normal

Excessive *

 

45 (90)

05 (10)

Signs and symptoms of PIH

Edema(feet) Headache Ringing  in ears

No specic sign

 

34(68)

04(8)

03(6)

09(18)

*discharge of p/v (excessive)-white, watery and odorless

outcomes, including preterm birth, intrauterine growth restriction (IUGR), perinatal death, acute renal or hepatic failure, antepartum haemorrhage,postpartum haemorrhage and maternal death. According to present study, nearly one fourth of mothers had age range 31 to 35

Table 3: Maternal outcomes of mothers

N=31

Variables f (%)
Gestational age at delivery(weeks)  
11(35.4)
33-36
37-40 20 (64.5)
Mode of delivery  
11 (35.4)
Vaginal Delivery
Cesarean Section 20 (64.5)
Perineal tear (1st degree) Yes 03 (9.7)
BP after delivery  
Normal 19 (61.2)
Pre hypertension 12(38.7)

Table 4 : Fetal outcomes  of subjects      N=31

Variables f  (%)
Gestational age of newborn (weeks)

<37

>37

11( 35.4)

20 (64.5)

Sex of Newborn

Male Female

20 (64.5)

11 (35.4)

APGAR at 1 min

7

8

9

10 (32.2)

15(48.3)

6 (19.3)

APGAR at 5 min

7

8

9

02 (6.4)

11 (35.4)

18 (58.06)

Initiation of breast feeding:(within)

Half an hour 6 hours

24 hours

06 (19.3)

17 (54.8)

08 (25.8)

Baby weight (kg )

1.5-2.0

2.1-2.5

>2.5

05 (16.1)

16(51.6)

10(32.2)

Admission in NICU

YES NO

21 (67.7)

10 (32.2)

Neonatal outcome

Healthy IUGR L BW

Death

10 (32.5)

04 (22.5)

15 (38.7)

02 (6.4)

 

years. A study by Lamminpaa et al stated that maternal age as an important factor. Pregnancy induced hypertension is common in rst pregnancy (primipara 40% as compared with 10 % in multipara) and women over the age of 30 years because of associated multiparty.2 E d e m a i s c o m m o n i n n o r m a l pregnancy, but generalized edema is a danger sign of preeclampsia. The present study results showed that only few mothers had +1 pedal edema. A study by Begum reported that cesarean sections (cases with PIH) were 3.8 times more, and also revealed PIH was associated with increased cesarean section. The greater the severity of HTN, the more are the complications associated with it during pregnancy.3 Zibaeenezhad et al. reported a 45.8% rate.4 In present study, more than half of pregnancies (64.5%) had been terminated by cesarean section.

Birth weight of newborn born to hypertensive mothers is lower than normal. The birth weight of babies born to chronically hypertensive  mothers  is  also l o w e r t h a n p r e g n a n c y – i n d u c e d hypertensive mothers. In present study, nearly about half of babies (16 out of 31) born to hypertensive mothers had birth weights less than 2500 gms. Out of the them, one third of newborns (10 out of 31) weighed less than 2000 gms. A study by Brown and Buddle reported fetal outcomes, out of 56 babies, 59% had appropriate weight in relation to their age and 66% had good APGAR score which substantiates the results of Chaim et al. who had 99.2% newborns with good APGAR score after 5

Conclusion:

Maternal and neonatal outcomes were good , may be because antenatal mothers were registered, supervised and delivered in tertiary care institution under supervision of expert obstetricians, neonatologists and nurses. Hence resulted into healthy mothers and neonates.

References

  1. Dutta DC. Textbook of Obstetrics.7th edition. Calcutta. New Central Book publications:
  2. Lamminpaa R, Julkunen K, Gissler M, H e i n o n e n S . P r e e c l a m p s i a complicated by advanced maternal age: A registry based study on primiparous women in Finland. 1997- BMC Pregnancy Childbirth 2012; 12(1):47. doi: 10.1186/1471- 2393-12-47.
  3. Begum A, Ganguly Rate  of C a e s a r e a n o p e r a t i o n a n d complications in hypertensive disorders of pregnancy. The ORION Medical Journal 2007;(27): 463-66.
  4. Zibaeenezhad, MJ, Ghodsi M, Arab P, Gholzom The Prevalence of Hypertensive Disorders of Pregnancy in Shiraz, Southern Iran. Iranian Cardiovascular Research Journal 2010;(4): 169-72
  5. Brown MA, Buddle Hypertension in pregnancy: Maternal and fetal outcomes according to laboratory and minutes of life.5,6 In present study. all clinical features. The Medical Journal newborns had good APGAR scores (>7) at 1 and 5 minutes. of Australia 1996 ;165(7): 360-65
  1. Chaim SP, Olivia SV, Kimura Pregnancy-induced hypertension and the neonatal outcome. Acta Paulista de Enfermagem(2008) [cited on 2017 O c t ] A v a i l a b l e f r o m : URL<http://dx.doi.org/10.1590/S010 3-21002008000100008>